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Assessment of Hepatic Cytochrome P450 3A Activity Using Metabolic Markers in Patients with Renal Impairment

BACKGROUND: The renal function of individuals is one of the reasons for the variations in therapeutic response to various drugs. Patients with renal impairment are often exposed to drug toxicity, even with drugs that are usually eliminated by hepatic metabolism. Previous study has reported an increa...

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Detalles Bibliográficos
Autores principales: Kim, Andrew HyoungJin, Yoon, Sumin, Lee, Yujin, Lee, Jieon, Bae, Eunjin, Lee, Hajeong, Kim, Dong Ki, Lee, SeungHwan, Yu, Kyung-sang, Jang, In-Jin, Cho, Joo-Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306325/
https://www.ncbi.nlm.nih.gov/pubmed/30595680
http://dx.doi.org/10.3346/jkms.2018.33.e298