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The enhancer RNA lnc-SLC4A1-1 epigenetically regulates unexplained recurrent pregnancy loss (URPL) by activating CXCL8 and NF-kB pathway

BACKGROUND: Enhancer RNAs (eRNAs) are a group of lncRNAs transcribed from enhancers, whose regulatory effects on gene expression are an emerging area of interest. However, the role of eRNAs in regulating trophoblast cells and unexplained recurrent pregnancy loss (URPL) remains elusive. METHODS: We p...

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Detalles Bibliográficos
Autores principales: Huang, Zhenyao, Du, Guizhen, Huang, Xiaomin, Han, Li, Han, Xiumei, Xu, Bo, Zhang, Yan, Yu, Mingming, Qin, Yufeng, Xia, Yankai, Wang, Xinru, Lu, Chuncheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306333/
https://www.ncbi.nlm.nih.gov/pubmed/30448228
http://dx.doi.org/10.1016/j.ebiom.2018.11.015