Proteolytic cleavage of amyloid precursor protein by ADAM10 mediates proliferation and migration in breast cancer

BACKGROUND: Amyloid precursor protein (APP), best known for its association with Alzheimer disease, has recently been implicated in breast cancer progression. However, the precise mechanism involved remains unclear. Here, we investigated the role of APP proteolytic cleavage in breast cancer function...

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Detalles Bibliográficos
Autores principales: Tsang, Julia Y.S., Lee, Michelle A., Chan, Tsz-Hei, Li, Joshua, Ni, Yun-Bi, Shao, Yan, Chan, Siu-Ki, Cheungc, Sai-Yin, Lau, Kwok-Fai, Tse, Gary M.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306343/
https://www.ncbi.nlm.nih.gov/pubmed/30470613
http://dx.doi.org/10.1016/j.ebiom.2018.11.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306343/
https://www.ncbi.nlm.nih.gov/pubmed/30470613
http://dx.doi.org/10.1016/j.ebiom.2018.11.012

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