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Chronic intermittent hypoxia disrupts cardiorespiratory homeostasis and gut microbiota composition in adult male guinea-pigs

BACKGROUND: Carotid body (peripheral oxygen sensor) sensitisation is pivotal in the development of chronic intermittent hypoxia (CIH)-induced hypertension. We sought to determine if exposure to CIH, modelling human sleep apnoea, adversely affects cardiorespiratory control in guinea-pigs, a species w...

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Detalles Bibliográficos
Autores principales: Lucking, Eric F., O'Connor, Karen M., Strain, Conall R., Fouhy, Fiona, Bastiaanssen, Thomaz F.S., Burns, David P., Golubeva, Anna V., Stanton, Catherine, Clarke, Gerard, Cryan, John F., O'Halloran, Ken D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306383/
https://www.ncbi.nlm.nih.gov/pubmed/30446434
http://dx.doi.org/10.1016/j.ebiom.2018.11.010