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Chronic intermittent hypoxia disrupts cardiorespiratory homeostasis and gut microbiota composition in adult male guinea-pigs
BACKGROUND: Carotid body (peripheral oxygen sensor) sensitisation is pivotal in the development of chronic intermittent hypoxia (CIH)-induced hypertension. We sought to determine if exposure to CIH, modelling human sleep apnoea, adversely affects cardiorespiratory control in guinea-pigs, a species w...
Autores principales: | Lucking, Eric F., O'Connor, Karen M., Strain, Conall R., Fouhy, Fiona, Bastiaanssen, Thomaz F.S., Burns, David P., Golubeva, Anna V., Stanton, Catherine, Clarke, Gerard, Cryan, John F., O'Halloran, Ken D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306383/ https://www.ncbi.nlm.nih.gov/pubmed/30446434 http://dx.doi.org/10.1016/j.ebiom.2018.11.010 |
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