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Hypoxia Impairs Initial Outgrowth of Endothelial Colony Forming Cells and Reduces Their Proliferative and Sprouting Potential

Vascular homeostasis and regeneration in ischemic tissue relies on intrinsic competence of the tissue to rapidly recruit endothelial cells for vascularization. The mononuclear cell (MNC) fraction of blood contains circulating progenitors committed to endothelial lineage. These progenitors give rise...

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Detalles Bibliográficos
Autores principales: Tasev, Dimitar, Dekker-Vroling, Laura, van Wijhe, Michiel, Broxterman, Henk J., Koolwijk, Pieter, van Hinsbergh, Victor W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306419/
https://www.ncbi.nlm.nih.gov/pubmed/30619865
http://dx.doi.org/10.3389/fmed.2018.00356