Why the Energy Landscape of Barnase Is Hierarchical

We have used NMR and computational methods to characterize the dynamics of the ribonuclease barnase over a wide range of timescales in free and inhibitor-bound states. Using temperature- and denaturant-dependent measurements of chemical shift, we show that barnase undergoes frequent and highly popul...

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Detalles Bibliográficos
Autores principales: Pandya, Maya J., Schiffers, Stefanie, Hounslow, Andrea M., Baxter, Nicola J., Williamson, Mike P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306431/
https://www.ncbi.nlm.nih.gov/pubmed/30619881
http://dx.doi.org/10.3389/fmolb.2018.00115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306431/
https://www.ncbi.nlm.nih.gov/pubmed/30619881
http://dx.doi.org/10.3389/fmolb.2018.00115

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