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TRH Analog, Taltirelin Protects Dopaminergic Neurons From Neurotoxicity of MPTP and Rotenone

Dopaminergic neurons loss is one of the main pathological characters of Parkinson’s disease (PD), while no suitable neuroprotective agents have been in clinical use. Thyrotropin-releasing hormone (TRH) and its analogs protect neurons from ischemia and various cytotoxins, but whether the effect also...

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Detalles Bibliográficos
Autores principales: Zheng, Cong, Chen, Guiqin, Tan, Yang, Zeng, Weiqi, Peng, Qiwei, Wang, Ji, Cheng, Chi, Yang, Xiaoman, Nie, Shuke, Xu, Yan, Zhang, Zhentao, Papa, Stella M., Ye, Keqiang, Cao, Xuebing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306470/
https://www.ncbi.nlm.nih.gov/pubmed/30618632
http://dx.doi.org/10.3389/fncel.2018.00485