An EGFR-mutated Lung Adenocarcinoma Undergoing Squamous Cell Carcinoma Transformation Exhibited a Durable Response to Afatinib

Squamous cell carcinoma (SCC) transformation has been identified as a mechanism of resistance to first-generation epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), gefitinib or erlotinib, in EGFR-mutated lung cancer. However, whether second- or third-generation TKIs can overco...

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Detalles Bibliográficos
Autores principales: Sato, Mitsuo, Matsui, Akira, Shimoyama, Yoshie, Omote, Norihito, Morise, Masahiro, Hase, Tetsunari, Tanaka, Ichidai, Suzuki, Kojiro, Hasegawa, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306534/
https://www.ncbi.nlm.nih.gov/pubmed/30101911
http://dx.doi.org/10.2169/internalmedicine.0999-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306534/
https://www.ncbi.nlm.nih.gov/pubmed/30101911
http://dx.doi.org/10.2169/internalmedicine.0999-18

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