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An EGFR-mutated Lung Adenocarcinoma Undergoing Squamous Cell Carcinoma Transformation Exhibited a Durable Response to Afatinib
Squamous cell carcinoma (SCC) transformation has been identified as a mechanism of resistance to first-generation epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), gefitinib or erlotinib, in EGFR-mutated lung cancer. However, whether second- or third-generation TKIs can overco...
Autores principales: | Sato, Mitsuo, Matsui, Akira, Shimoyama, Yoshie, Omote, Norihito, Morise, Masahiro, Hase, Tetsunari, Tanaka, Ichidai, Suzuki, Kojiro, Hasegawa, Yoshinori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306534/ https://www.ncbi.nlm.nih.gov/pubmed/30101911 http://dx.doi.org/10.2169/internalmedicine.0999-18 |
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