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Defective Vagal Innervation in Murine Tbx1 Mutant Hearts

Haploinsufficiency of the T-box transcription factor TBX1 is responsible for many features of 22q11.2 deletion syndrome. Tbx1 is expressed dynamically in the pharyngeal apparatus during mouse development and Tbx1 homozygous mutants display numerous severe defects including abnormal cranial ganglion...

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Detalles Bibliográficos
Autores principales: Calmont, Amélie, Anderson, Naomi, Suntharalingham, Jenifer P., Ang, Richard, Tinker, Andrew, Scambler, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306933/
https://www.ncbi.nlm.nih.gov/pubmed/30249045
http://dx.doi.org/10.3390/jcdd5040049