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In Silico Profiling of Clinical Phenotypes for Human Targets Using Adverse Event Data

We present a novel approach for the molecular transformation and analysis of patient clinical phenotypes. Building on the fact that drugs perturb the function of targets/genes, we integrated data from 8.2 million clinical reports detailing drug-induced side effects with the molecular world of drug-t...

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Detalles Bibliográficos
Autores principales: Soldatos, Theodoros G., Taglang, Guillaume, Jackson, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306940/
https://www.ncbi.nlm.nih.gov/pubmed/30477159
http://dx.doi.org/10.3390/ht7040037