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In Silico Profiling of Clinical Phenotypes for Human Targets Using Adverse Event Data
We present a novel approach for the molecular transformation and analysis of patient clinical phenotypes. Building on the fact that drugs perturb the function of targets/genes, we integrated data from 8.2 million clinical reports detailing drug-induced side effects with the molecular world of drug-t...
Autores principales: | Soldatos, Theodoros G., Taglang, Guillaume, Jackson, David B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306940/ https://www.ncbi.nlm.nih.gov/pubmed/30477159 http://dx.doi.org/10.3390/ht7040037 |
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