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Lactoferrin ameliorates dopaminergic neurodegeneration and motor deficits in MPTP-treated mice

Brain iron accumulation is common in patients with Parkinson's disease (PD). Iron chelators have been investigated for their ability to prevent neurodegenerative diseases with features of iron overload. Given the non-trivial side effects of classical iron chelators, lactoferrin (Lf), a multifun...

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Detalles Bibliográficos
Autores principales: Xu, Shuang-Feng, Zhang, Yan-Hui, Wang, Shan, Pang, Zhong-Qiu, Fan, Yong-Gang, Li, Jia-Yi, Wang, Zhan-You, Guo, Chuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307097/
https://www.ncbi.nlm.nih.gov/pubmed/30593976
http://dx.doi.org/10.1016/j.redox.2018.101090