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Optimization of Zika virus envelope protein production for ELISA and correlation of antibody titers with virus neutralization in Mexican patients from an arbovirus endemic region

BACKGROUND: Zika virus (ZIKV) has become a global threat with immediate need for accurate diagnostics, efficacious vaccines and therapeutics. Several ZIKV envelope (Env)-based vaccines have been developed recently. However, many commercially available ZIKV Env are based on the African lineage and pr...

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Detalles Bibliográficos
Autores principales: Kim, Young Chan, Lopez-Camacho, Cesar, Nettleship, Joanne E., Rahman, Nahid, Hill, Michelle L., Silva-Reyes, Laura, Ortiz-Martinez, Georgina, Figueroa-Aguilar, Gloria, Mar, María Antonieta, Vivanco-Cid, Héctor, Rollier, Christine S., Zitzmann, Nicole, Viveros-Sandoval, Martha Eva, Owens, Raymond J., Reyes-Sandoval, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307127/
https://www.ncbi.nlm.nih.gov/pubmed/30587198
http://dx.doi.org/10.1186/s12985-018-1104-6