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Discerning novel splice junctions derived from RNA-seq alignment: a deep learning approach

BACKGROUND: Exon splicing is a regulated cellular process in the transcription of protein-coding genes. Technological advancements and cost reductions in RNA sequencing have made quantitative and qualitative assessments of the transcriptome both possible and widely available. RNA-seq provides unprec...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Liu, Xinan, MacLeod, James, Liu, Jinze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307148/
https://www.ncbi.nlm.nih.gov/pubmed/30591034
http://dx.doi.org/10.1186/s12864-018-5350-1