Lifestyle modifications: coordinating the tRNA epitranscriptome with codon bias to adapt translation during stress responses

Cells adapt to stress by altering gene expression at multiple levels. Here, we propose a new mechanism regulating stress-dependent gene expression at the level of translation, with coordinated interplay between the tRNA epitranscriptome and biased codon usage in families of stress-response genes. In...

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Detalles Bibliográficos
Autores principales: Chan, Cheryl, Pham, Phuong, Dedon, Peter C., Begley, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307160/
https://www.ncbi.nlm.nih.gov/pubmed/30587213
http://dx.doi.org/10.1186/s13059-018-1611-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307160/
https://www.ncbi.nlm.nih.gov/pubmed/30587213
http://dx.doi.org/10.1186/s13059-018-1611-1

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