Hepatocellular carcinoma-derived exosomal miRNA-21 contributes to tumor progression by converting hepatocyte stellate cells to cancer-associated fibroblasts

BACKGROUND: Hepatocellular carcinoma (HCC) remains a global challenge due to its high morbidity and mortality rates as well as poor response to treatment. The communication between tumor-derived elements and stroma plays a critical role in facilitating cancer progression of HCC. Exosomes are small e...

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Detalles Bibliográficos
Autores principales: Zhou, Yuan, Ren, Haozhen, Dai, Bo, Li, Jun, Shang, Longcheng, Huang, Jianfei, Shi, Xiaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307162/
https://www.ncbi.nlm.nih.gov/pubmed/30591064
http://dx.doi.org/10.1186/s13046-018-0965-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307162/
https://www.ncbi.nlm.nih.gov/pubmed/30591064
http://dx.doi.org/10.1186/s13046-018-0965-2

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