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SMARTcleaner: identify and clean off-target signals in SMART ChIP-seq analysis

BACKGROUND: Noises and artifacts may arise in several steps of the next-generation sequencing (NGS) process. Recently, an NGS library preparation method called SMART, or Switching Mechanism At the 5′ end of the RNA Transcript, is introduced to prepare ChIP-seq (chromatin immunoprecipitation and deep...

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Detalles Bibliográficos
Autores principales: Zhao, Dejian, Zheng, Deyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307164/
https://www.ncbi.nlm.nih.gov/pubmed/30587107
http://dx.doi.org/10.1186/s12859-018-2577-4