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SMARTcleaner: identify and clean off-target signals in SMART ChIP-seq analysis
BACKGROUND: Noises and artifacts may arise in several steps of the next-generation sequencing (NGS) process. Recently, an NGS library preparation method called SMART, or Switching Mechanism At the 5′ end of the RNA Transcript, is introduced to prepare ChIP-seq (chromatin immunoprecipitation and deep...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307164/ https://www.ncbi.nlm.nih.gov/pubmed/30587107 http://dx.doi.org/10.1186/s12859-018-2577-4 |