Genome rearrangements in Escherichia coli during de novo acquisition of resistance to a single antibiotic or two antibiotics successively

BACKGROUND: The ability of bacteria to acquire resistance to antibiotics relies to a large extent on their capacity for genome modification. Prokaryotic genomes are highly plastic and can utilize horizontal gene transfer, point mutations, and gene deletions or amplifications to realize genome expans...

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Detalles Bibliográficos
Autores principales: Hoeksema, Marloes, Jonker, Martijs J., Bel, Keshia, Brul, Stanley, ter Kuile, Benno H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307192/
https://www.ncbi.nlm.nih.gov/pubmed/30591014
http://dx.doi.org/10.1186/s12864-018-5353-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307192/
https://www.ncbi.nlm.nih.gov/pubmed/30591014
http://dx.doi.org/10.1186/s12864-018-5353-y

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