Macrophage-Derived miRNA-Containing Exosomes Induce Peritendinous Fibrosis after Tendon Injury through the miR-21-5p/Smad7 Pathway

Following tendon injury, the development of fibrotic healing response impairs tendon function and restricts tendon motion. Peritendinous tissue fibrosis poses a major clinical problem in hand surgery. Communication between macrophages and tendon cells has a critical role in regulating the tendon-hea...

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Detalles Bibliográficos
Autores principales: Cui, Haomin, He, Yu, Chen, Shuai, Zhang, Deming, Yu, Yaling, Fan, Cunyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307349/
https://www.ncbi.nlm.nih.gov/pubmed/30594070
http://dx.doi.org/10.1016/j.omtn.2018.11.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307349/
https://www.ncbi.nlm.nih.gov/pubmed/30594070
http://dx.doi.org/10.1016/j.omtn.2018.11.006

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