miR675 Accelerates Malignant Transformation of Mesenchymal Stem Cells by Blocking DNA Mismatch Repair

miR675 is highly expressed in several human tumor tissues and positively regulates cell progression. Herein, we demonstrate that miR675 promotes malignant transformation of human mesenchymal stem cells. Mechanistically, we reveal that miR675 enhances the expression of the polyubiquitin-binding prote...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Yanan, Song, Shuting, Jiang, Xiaoxue, Meng, Qiuyu, Wang, Chen, Li, Xiaonan, Yang, Yuxin, Xin, Xiaoru, Zheng, Qidi, Wang, Liyan, Pu, Hu, Gui, Xin, Li, Tianming, Lu, Dongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307386/
https://www.ncbi.nlm.nih.gov/pubmed/30594073
http://dx.doi.org/10.1016/j.omtn.2018.11.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307386/
https://www.ncbi.nlm.nih.gov/pubmed/30594073
http://dx.doi.org/10.1016/j.omtn.2018.11.010

Ejemplares similares