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miR675 Accelerates Malignant Transformation of Mesenchymal Stem Cells by Blocking DNA Mismatch Repair
miR675 is highly expressed in several human tumor tissues and positively regulates cell progression. Herein, we demonstrate that miR675 promotes malignant transformation of human mesenchymal stem cells. Mechanistically, we reveal that miR675 enhances the expression of the polyubiquitin-binding prote...
Autores principales: | Lu, Yanan, Song, Shuting, Jiang, Xiaoxue, Meng, Qiuyu, Wang, Chen, Li, Xiaonan, Yang, Yuxin, Xin, Xiaoru, Zheng, Qidi, Wang, Liyan, Pu, Hu, Gui, Xin, Li, Tianming, Lu, Dongdong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307386/ https://www.ncbi.nlm.nih.gov/pubmed/30594073 http://dx.doi.org/10.1016/j.omtn.2018.11.010 |
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