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PDE5 inhibitor protects the mitochondrial function of hypoxic myocardial cells

Protective effect of phosphodiesterase 5 (PDE5) inhibitor sildenafil on hypoxic injury of isolated myocardial cells and its mechanism of action were investigated. Myocardial cells of neonatal mice were isolated, cultured and divided into blank, control, and PDE5 inhibitor group. Cells in the control...

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Detalles Bibliográficos
Autores principales: Jia, Haiyan, Guo, Zhen, Yao, Yanfen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307451/
https://www.ncbi.nlm.nih.gov/pubmed/30651783
http://dx.doi.org/10.3892/etm.2018.6951