Naldemedine in Japanese patients with opioid-induced constipation and chronic noncancer pain: open-label Phase III studies

INTRODUCTION: Naldemedine is a peripherally-acting µ-opioid-receptor antagonist, approved in Japan for opioid-induced constipation (OIC). In two open-label, single-arm, Phase III studies, we evaluated the safety and efficacy of naldemedine in Japanese patients with OIC receiving regular-use opioids...

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Detalles Bibliográficos
Autores principales: Saito, Yoji, Yokota, Takaaki, Arai, Masatsugu, Tada, Yukio, Sumitani, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307491/
https://www.ncbi.nlm.nih.gov/pubmed/30613161
http://dx.doi.org/10.2147/JPR.S175900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307491/
https://www.ncbi.nlm.nih.gov/pubmed/30613161
http://dx.doi.org/10.2147/JPR.S175900

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