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Safety of oral methylnaltrexone for opioid-induced constipation in patients with chronic noncancer pain
PURPOSE: Oral methylnaltrexone was shown to be effective in treating opioid-induced constipation (OIC) in patients with chronic noncancer pain in a Phase III randomized controlled trial. This report provides a detailed safety analysis from that study. METHODS: Adults (n=803) with chronic noncancer p...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307492/ https://www.ncbi.nlm.nih.gov/pubmed/30613162 http://dx.doi.org/10.2147/JPR.S170086 |