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Safety of oral methylnaltrexone for opioid-induced constipation in patients with chronic noncancer pain

PURPOSE: Oral methylnaltrexone was shown to be effective in treating opioid-induced constipation (OIC) in patients with chronic noncancer pain in a Phase III randomized controlled trial. This report provides a detailed safety analysis from that study. METHODS: Adults (n=803) with chronic noncancer p...

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Detalles Bibliográficos
Autores principales: Rauck, Richard L, Slatkin, Neal E, Stambler, Nancy, Israel, Robert J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307492/
https://www.ncbi.nlm.nih.gov/pubmed/30613162
http://dx.doi.org/10.2147/JPR.S170086