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Safety of oral methylnaltrexone for opioid-induced constipation in patients with chronic noncancer pain

PURPOSE: Oral methylnaltrexone was shown to be effective in treating opioid-induced constipation (OIC) in patients with chronic noncancer pain in a Phase III randomized controlled trial. This report provides a detailed safety analysis from that study. METHODS: Adults (n=803) with chronic noncancer p...

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Detalles Bibliográficos
Autores principales:	Rauck, Richard L, Slatkin, Neal E, Stambler, Nancy, Israel, Robert J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307492/ https://www.ncbi.nlm.nih.gov/pubmed/30613162 http://dx.doi.org/10.2147/JPR.S170086

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