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The HMGB1-RAGE/TLR-TNF-α signaling pathway may contribute to kidney injury induced by hypoxia

The hypoxia-reoxygenation process of obstructive sleep apnea (OSA) may cause oxidative stress injury of the kidney, but the molecular mechanisms are not clear. The present study aimed to investigate whether high mobility group box 1 protein (HMGB1) and its subsequent inflammatory pathway served a ro...

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Detalles Bibliográficos
Autores principales: Zhang, Cheng, Dong, Hui, Chen, Fengwei, Wang, Yunxia, Ma, Jing, Wang, Guangfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307518/
https://www.ncbi.nlm.nih.gov/pubmed/30651760
http://dx.doi.org/10.3892/etm.2018.6932