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Oncologic Outcomes in Metastatic Colorectal Cancer with Regorafenib with FOLFIRI as a Third- or Fourth-Line Setting()()()

BACKGROUND: To evaluate the efficacy and toxicities of regorafenib plus irinotecan, dose-escalated on the basis of uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) genotyping, in previously heavily treated metastatic colorectal cancer (mCRC) and the prognostic values of EGFR expression, KRAS...

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Detalles Bibliográficos
Autores principales: Ma, Cheng-Jen, Huang, Ching-Wen, Chang, Tsung-Kun, Tsai, Hsiang-Lin, Su, Wei-Chih, Yeh, Yung-Sung, Chen, Po-Jung, Wang, Jaw-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307535/
https://www.ncbi.nlm.nih.gov/pubmed/30594039
http://dx.doi.org/10.1016/j.tranon.2018.12.003