Profiles of metabolic gene expression in the white adipose tissue, liver and hypothalamus in leptin knockout (Lep(ΔI14/ΔI14) ) rats

Leptin deficiency is principally linked to metabolic disorders. Leptin knockout (Lep(ΔI14/ΔI14)) Sprague Dawley rats created by CRISPR/Cas9 is a new model to study metabolic disorders. We used a whole rat genome oligonucleotide microarray to obtain tissue-specific gene expression profiles of the whi...

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Detalles Bibliográficos
Autores principales: Guan, Leijian, Xu, Kaixuan, Xu, Shuyang, Li, Ningning, Wang, Xinru, Xia, Yankai, Wu, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307666/
https://www.ncbi.nlm.nih.gov/pubmed/28866659
http://dx.doi.org/10.7555/JBR.31.20170021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307666/
https://www.ncbi.nlm.nih.gov/pubmed/28866659
http://dx.doi.org/10.7555/JBR.31.20170021

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