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Overexpression of PDK4 is associated with cell proliferation, drug resistance and poor prognosis in ovarian cancer

PURPOSE: Ovarian cancer is a major type of gynecological malignancy which characterized by the chemoresistance, heterogeneity and highly metastasis. However, the mechanism underlying the progression of ovarian cancer remains elusive. Pyruvate dehydrogenase kinase family plays critical roles in tumor...

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Detalles Bibliográficos
Autores principales: Wang, Jinghao, Qian, Yu, Gao, Meiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307676/
https://www.ncbi.nlm.nih.gov/pubmed/30636897
http://dx.doi.org/10.2147/CMAR.S185015