Toll-like receptor-2 regulates macrophage polarization induced by excretory-secretory antigens from Schistosoma japonicum eggs and promotes liver pathology in murine schistosomiasis

Schistosomiasis is endemic to many regions of the world and affects approximately 200 million people. Conventional adaptive T cell responses are considered to be the primary contributors to the pathogenesis of Schistosoma japonicum infection, leading to liver granuloma and fibrosis. However, the fun...

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Detalles Bibliográficos
Autores principales: Gong, Wenci, Huang, Fengjuan, Sun, Lei, Yu, Aiping, Zhang, Xiaofan, Xu, Yuxin, Shen, Yujuan, Cao, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307705/
https://www.ncbi.nlm.nih.gov/pubmed/30589840
http://dx.doi.org/10.1371/journal.pntd.0007000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307705/
https://www.ncbi.nlm.nih.gov/pubmed/30589840
http://dx.doi.org/10.1371/journal.pntd.0007000

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