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Active degradation of MarA controls coordination of its downstream targets

Several key transcription factors have unusually short half-lives compared to other cellular proteins. Here, we explore the utility of active degradation in shaping how the multiple antibiotic resistance activator MarA coordinates its downstream targets. MarA controls a variety of stress response ge...

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Detalles Bibliográficos
Autores principales: Rossi, Nicholas A., Mora, Thierry, Walczak, Aleksandra M., Dunlop, Mary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307708/
https://www.ncbi.nlm.nih.gov/pubmed/30589845
http://dx.doi.org/10.1371/journal.pcbi.1006634