Different functional states of fusion protein gB revealed on human cytomegalovirus by cryo electron tomography with Volta phase plate

Human cytomegalovirus (HCMV) enters host by glycoprotein B (gB)-mediated membrane fusion upon receptor-binding to gH/gL-related complexes, causing devastating diseases such as birth defects. Although an X-ray crystal structure of the recombinant gB ectodomain at postfusion conformation is available,...

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Detalles Bibliográficos
Autores principales: Si, Zhu, Zhang, Jiayan, Shivakoti, Sakar, Atanasov, Ivo, Tao, Chang-Lu, Hui, Wong H., Zhou, Kang, Yu, Xuekui, Li, Weike, Luo, Ming, Bi, Guo-Qiang, Zhou, Z. Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307773/
https://www.ncbi.nlm.nih.gov/pubmed/30507948
http://dx.doi.org/10.1371/journal.ppat.1007452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307773/
https://www.ncbi.nlm.nih.gov/pubmed/30507948
http://dx.doi.org/10.1371/journal.ppat.1007452

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