Advanced glycation end products‐related modulation of cathepsin L and NF‐κB signalling effectors in retinal pigment epithelium lead to augmented response to TNFα

The retinal pigment epithelium (RPE) plays a central role in neuroretinal homoeostasis throughout life. Altered proteolysis and inflammatory processes involving RPE contribute to the pathophysiology of age‐related macular degeneration (AMD), but the link between these remains elusive. We report for...

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Detalles Bibliográficos
Autores principales: Sharif, Umar, Mahmud, Nur Musfirah, Kay, Paul, Yang, Yit C., Harding, Simon P., Grierson, Ian, Kamalden, Tengku Ain, Jackson, Malcolm J., Paraoan, Luminita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307775/
https://www.ncbi.nlm.nih.gov/pubmed/30338926
http://dx.doi.org/10.1111/jcmm.13944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307775/
https://www.ncbi.nlm.nih.gov/pubmed/30338926
http://dx.doi.org/10.1111/jcmm.13944

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