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Melatonin protects vertebral endplate chondrocytes against apoptosis and calcification via the Sirt1‐autophagy pathway

Melatonin is reportedly associated with intervertebral disc degeneration (IDD). Endplate cartilage is vitally important to intervertebral discs in physiological and pathological conditions. However, the effects and mechanism of melatonin on endplate chondrocytes (EPCs) are still unclear. Herein, we...

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Detalles Bibliográficos
Autores principales: Zhang, Zengjie, Lin, Jialiang, Tian, Naifeng, Wu, Yaosen, Zhou, Yifei, Wang, Chenggui, Wang, Qingqing, Jin, Haiming, Chen, Tingting, Nisar, Majid, Zheng, Gang, Xu, Tianzhen, Gao, Weiyang, Zhang, Xiaolei, Wang, Xiangyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307776/
https://www.ncbi.nlm.nih.gov/pubmed/30353656
http://dx.doi.org/10.1111/jcmm.13903