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3‐Cl‐AHPC inhibits pro‐HGF maturation by inducing matriptase/HAI‐1 complex formation

Matriptase is an epithelia‐specific membrane‐anchored serine protease, and its dysregulation is highly related to the progression of a variety of cancers. Hepatocyte growth factor activator inhibitor‐1 (HAI‐1) inhibits matriptase activity through forming complex with activated matriptase. The balanc...

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Detalles Bibliográficos
Autores principales: Ye, Fang, Chen, Shuang, Liu, Xingxing, Ye, Xiaohong, Wang, Keqi, Zeng, Zhiping, Su, Ying, Zhang, Xiao‐kun, Zhou, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307790/
https://www.ncbi.nlm.nih.gov/pubmed/30370662
http://dx.doi.org/10.1111/jcmm.13900