Liraglutide protects against glucolipotoxicity‐induced RIN‐m5F β‐cell apoptosis through restoration of PDX1 expression

Prolonged exposure to high levels of glucose and fatty acid (FFA) can induce tissue damage commonly referred to as glucolipotoxicity and is particularly harmful to pancreatic β‐cells. Glucolipotoxicity‐mediated β‐cell failure is a critical causal factor in the late stages of diabetes, which suggests...

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Detalles Bibliográficos
Autores principales: Kornelius, Edy, Li, Hsin‐Hua, Peng, Chiung‐Huei, Yang, Yi‐Sun, Chen, Wei‐Jen, Chang, Yan‐Zin, Bai, Yi‐Chiao, Liu, Stanley, Huang, Chien‐Ning, Lin, Chih‐Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307795/
https://www.ncbi.nlm.nih.gov/pubmed/30353648
http://dx.doi.org/10.1111/jcmm.13967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307795/
https://www.ncbi.nlm.nih.gov/pubmed/30353648
http://dx.doi.org/10.1111/jcmm.13967

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