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Trans‐repression of NFκB pathway mediated by PPARγ improves vascular endothelium insulin resistance

Previous study has shown that thiazolidinediones (TZDs) improved endothelium insulin resistance (IR) induced by high glucose concentration (HG)/hyperglycaemia through a PPARγ‐dependent‐NFκB trans‐repression mechanism. However, it is unclear, whether changes in PPARγ expression affect the endothelium...

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Detalles Bibliográficos
Autores principales: Kong, Ying, Gao, Yan, Lan, Dongyi, Zhang, Ying, Zhan, Rixin, Liu, Meiqi, Zhu, Zhouan, Zeng, Guohua, Huang, Qiren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307800/
https://www.ncbi.nlm.nih.gov/pubmed/30398029
http://dx.doi.org/10.1111/jcmm.13913