Deciphering the molecular effects of romidepsin on germ cell tumours: DHRS2 is involved in cell cycle arrest but not apoptosis or induction of romidepsin effectors

Testicular germ cell tumours (GCTs) mostly affect young men at age 17‐40. Although high cure rates can be achieved by orchiectomy and chemotherapy, GCTs can still be a lethal threat to young patients with metastases or therapy resistance. Thus, alternative treatment options are needed. Based on stud...

Descripción completa

Detalles Bibliográficos
Autores principales: Nettersheim, Daniel, Berger, Daniel, Jostes, Sina, Skowron, Margaretha, Schorle, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307807/
https://www.ncbi.nlm.nih.gov/pubmed/30460772
http://dx.doi.org/10.1111/jcmm.13971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307807/
https://www.ncbi.nlm.nih.gov/pubmed/30460772
http://dx.doi.org/10.1111/jcmm.13971

Ejemplares similares