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Different behaviour of DVL1, DVL2, DVL3 in astrocytoma malignancy grades and their association to TCF1 and LEF1 upregulation

Key regulators of the Wnt signalling, DVL1, DVL2 and DVL3, in astrocytomas of different malignancy grades were investigated. Markers for DVL1,DVL2 and DVL3 were used to detect microsatellite instability (MSI) and gross deletions (LOH), while immunohistochemistry and immunoreactivity score were used...

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Detalles Bibliográficos
Autores principales: Kafka, Anja, Bačić, Mateja, Tomas, Davor, Žarković, Kamelija, Bukovac, Anja, Njirić, Niko, Mrak, Goran, Krsnik, Željka, Pećina‐Šlaus, Nives
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307814/
https://www.ncbi.nlm.nih.gov/pubmed/30468298
http://dx.doi.org/10.1111/jcmm.13969