Conserved mRNA-granule component Scd6 targets Dhh1 to repress translation initiation and activates Dcp2-mediated mRNA decay in vivo

Scd6 protein family members are evolutionarily conserved components of translationally silent mRNA granules. Yeast Scd6 interacts with Dcp2 and Dhh1, respectively a subunit and a regulator of the mRNA decapping enzyme, and also associates with translation initiation factor eIF4G to inhibit translati...

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Detalles Bibliográficos
Autores principales: Zeidan, Quira, He, Feng, Zhang, Fan, Zhang, Hongen, Jacobson, Allan, Hinnebusch, Alan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307823/
https://www.ncbi.nlm.nih.gov/pubmed/30532217
http://dx.doi.org/10.1371/journal.pgen.1007806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307823/
https://www.ncbi.nlm.nih.gov/pubmed/30532217
http://dx.doi.org/10.1371/journal.pgen.1007806

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