TAPBPR mediates peptide dissociation from MHC class I using a leucine lever

Tapasin and TAPBPR are known to perform peptide editing on major histocompatibility complex class I (MHC I) molecules; however, the precise molecular mechanism(s) involved in this process remain largely enigmatic. Here, using immunopeptidomics in combination with novel cell-based assays that assess...

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Detalles Bibliográficos
Autores principales: Ilca, F Tudor, Neerincx, Andreas, Hermann, Clemens, Marcu, Ana, Stevanović, Stefan, Deane, Janet E, Boyle, Louise H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307860/
https://www.ncbi.nlm.nih.gov/pubmed/30484775
http://dx.doi.org/10.7554/eLife.40126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307860/
https://www.ncbi.nlm.nih.gov/pubmed/30484775
http://dx.doi.org/10.7554/eLife.40126

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