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Muscle-specific stress fibers give rise to sarcomeres in cardiomyocytes

The sarcomere is the contractile unit within cardiomyocytes driving heart muscle contraction. We sought to test the mechanisms regulating actin and myosin filament assembly during sarcomere formation. Therefore, we developed an assay using human cardiomyocytes to monitor sarcomere assembly. We repor...

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Detalles Bibliográficos
Autores principales: Fenix, Aidan M, Neininger, Abigail C, Taneja, Nilay, Hyde, Karren, Visetsouk, Mike R, Garde, Ryan J, Liu, Baohong, Nixon, Benjamin R, Manalo, Annabelle E, Becker, Jason R, Crawley, Scott W, Bader, David M, Tyska, Matthew J, Liu, Qi, Gutzman, Jennifer H, Burnette, Dylan T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307863/
https://www.ncbi.nlm.nih.gov/pubmed/30540249
http://dx.doi.org/10.7554/eLife.42144