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Muscle-specific stress fibers give rise to sarcomeres in cardiomyocytes
The sarcomere is the contractile unit within cardiomyocytes driving heart muscle contraction. We sought to test the mechanisms regulating actin and myosin filament assembly during sarcomere formation. Therefore, we developed an assay using human cardiomyocytes to monitor sarcomere assembly. We repor...
Autores principales: | Fenix, Aidan M, Neininger, Abigail C, Taneja, Nilay, Hyde, Karren, Visetsouk, Mike R, Garde, Ryan J, Liu, Baohong, Nixon, Benjamin R, Manalo, Annabelle E, Becker, Jason R, Crawley, Scott W, Bader, David M, Tyska, Matthew J, Liu, Qi, Gutzman, Jennifer H, Burnette, Dylan T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307863/ https://www.ncbi.nlm.nih.gov/pubmed/30540249 http://dx.doi.org/10.7554/eLife.42144 |
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