Dietary advanced glycation end-product consumption leads to mechanical stiffening of murine intervertebral discs

Back pain is a leading cause of disability and is strongly associated with intervertebral disc (IVD) degeneration. Reducing structural disruption and catabolism in IVD degeneration remains an important clinical challenge. Pro-oxidant and structure-modifying advanced glycation end-products (AGEs) con...

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Detalles Bibliográficos
Autores principales: Krishnamoorthy, Divya, Hoy, Robert C., Natelson, Devorah M., Torre, Olivia M., Laudier, Damien M., Iatridis, James C., Illien-Jünger, Svenja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307905/
https://www.ncbi.nlm.nih.gov/pubmed/30498097
http://dx.doi.org/10.1242/dmm.036012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307905/
https://www.ncbi.nlm.nih.gov/pubmed/30498097
http://dx.doi.org/10.1242/dmm.036012

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