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Dietary advanced glycation end-product consumption leads to mechanical stiffening of murine intervertebral discs
Back pain is a leading cause of disability and is strongly associated with intervertebral disc (IVD) degeneration. Reducing structural disruption and catabolism in IVD degeneration remains an important clinical challenge. Pro-oxidant and structure-modifying advanced glycation end-products (AGEs) con...
Autores principales: | Krishnamoorthy, Divya, Hoy, Robert C., Natelson, Devorah M., Torre, Olivia M., Laudier, Damien M., Iatridis, James C., Illien-Jünger, Svenja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307905/ https://www.ncbi.nlm.nih.gov/pubmed/30498097 http://dx.doi.org/10.1242/dmm.036012 |
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