A viable hypomorphic Arnt2 mutation causes hyperphagic obesity, diabetes and hepatic steatosis

Aryl hydrocarbon receptor nuclear translocator 2 (ARNT2) is a member of the basic helix-loop-helix/PER-ARNT-SIM (bHLH/PAS) transcription factor family. ARNT2 heterodimerizes with several members of the family, including single-minded homolog-1 (SIM1) and neuronal PAS domain protein 4 (NPAS4), primar...

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Detalles Bibliográficos
Autores principales: Turer, Emre E., San Miguel, Miguel, Wang, Kuan-wen, McAlpine, William, Ou, Feiya, Li, Xiaohong, Tang, Miao, Zang, Zhao, Wang, Jianhui, Hayse, Braden, Evers, Bret, Zhan, Xiaoming, Russell, Jamie, Beutler, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307907/
https://www.ncbi.nlm.nih.gov/pubmed/30563851
http://dx.doi.org/10.1242/dmm.035451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307907/
https://www.ncbi.nlm.nih.gov/pubmed/30563851
http://dx.doi.org/10.1242/dmm.035451

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