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A viable hypomorphic Arnt2 mutation causes hyperphagic obesity, diabetes and hepatic steatosis
Aryl hydrocarbon receptor nuclear translocator 2 (ARNT2) is a member of the basic helix-loop-helix/PER-ARNT-SIM (bHLH/PAS) transcription factor family. ARNT2 heterodimerizes with several members of the family, including single-minded homolog-1 (SIM1) and neuronal PAS domain protein 4 (NPAS4), primar...
Autores principales: | Turer, Emre E., San Miguel, Miguel, Wang, Kuan-wen, McAlpine, William, Ou, Feiya, Li, Xiaohong, Tang, Miao, Zang, Zhao, Wang, Jianhui, Hayse, Braden, Evers, Bret, Zhan, Xiaoming, Russell, Jamie, Beutler, Bruce |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307907/ https://www.ncbi.nlm.nih.gov/pubmed/30563851 http://dx.doi.org/10.1242/dmm.035451 |
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