An airway epithelial IL-17A response signature identifies a steroid-unresponsive COPD patient subgroup

BACKGROUND. Chronic obstructive pulmonary disease (COPD) is a heterogeneous smoking-related disease characterized by airway obstruction and inflammation. This inflammation may persist even after smoking cessation and responds variably to corticosteroids. Personalizing treatment to biologically simil...

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Detalles Bibliográficos
Autores principales: Christenson, Stephanie A., van den Berge, Maarten, Faiz, Alen, Inkamp, Kai, Bhakta, Nirav, Bonser, Luke R., Zlock, Lorna T., Barjaktarevic, Igor Z., Barr, R. Graham, Bleecker, Eugene R., Boucher, Richard C., Bowler, Russell P., Comellas, Alejandro P., Curtis, Jeffrey L., Han, MeiLan K., Hansel, Nadia N., Hiemstra, Pieter S., Kaner, Robert J., Krishnanm, Jerry A., Martinez, Fernando J., O’Neal, Wanda K., Paine, Robert, Timens, Wim, Wells, J. Michael, Spira, Avrum, Erle, David J., Woodruff, Prescott G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2018
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307967/
https://www.ncbi.nlm.nih.gov/pubmed/30383540
http://dx.doi.org/10.1172/JCI121087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307967/
https://www.ncbi.nlm.nih.gov/pubmed/30383540
http://dx.doi.org/10.1172/JCI121087

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